The second paper, published in 2018, discusses how certain organophosphorus compounds can induce apoptosis, particularly in neurons and myocardial cells, a process not reliant on cholinesterase inhibition.
The third article is a review summarizing the non-cholinergic toxic mechanisms of organophosphorus compounds discovered over the past decade, including oxidative stress, mitochondrial dysfunction, and neuroinflammatory responses.
Zhaxi grew more alarmed as he read, for if these articles were true, the clinical manifestations of organophosphorus poisoning are far more complex than written in clinical and forensic medicine textbooks. Symptoms like pupil constriction, salivation, and sweating might just be the tip of the iceberg. Beneath the surface, more unseen damage occurs, cells die, mitochondria collapse, and the nervous system slowly gets eroded.
