Firstly the target supreme needed to be in a weakened state. Against a completely fine supreme, the success rate of this method was abysmally low. But against a weakened supreme, this chance would shot up.
Firstly, a skill would be used on the supreme. The name of this skill was "Blessing of Transcendent". This was a positive skill that was always effective. Resisting or blocking it was close to impossible because it had no negative effects at all.
Then a very special material would be used. This material called Stella Regina was something that Zeta was familiar with. It was something that was created as a byproduct when the universe had started to develop its own origin energy.
This material had similar effect like the Chaos energy but without any benefits. So it just made people who had no affinity for the Chaos to feel weaker and terrible. This effect made this material a very potent poison. One of the very few that was effective on even a supreme.
